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Cheap flights Medellin — Panama City

Medellin (MDE, CO) Panama City (PTY, PA)
from $181 532 km ~1h 8m 10 flights found 2 airlines cheapest on Tuesday
Reverse route
How many travellers?
Adults
12+ years
1
Children
2–11 years
0
Infants
under 2
0
Choose your departure date
Cheapest: $181 on 17.11.2026
Prices shown are from searches by other travellers over the last 24 hours. Missing a date? Click any day — we'll find tickets anyway.
November 2026
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December 2026
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January 2027
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Prices found for 15 of 90 days. Prices update as more travellers search. Click any date to search live.
Depart
—
Return
—
Cheapest flights found
17 Nov 2026, Tue
Copa Airlines CM 757
18:45
MDE Jose Maria Cordova International Airport
20:14
PTY Tocumen International Airport
1h 29m Direct
Tickets
$181
View this ticket
26 Nov 2026, Thu
Copa Airlines CM 157
02:25
MDE Jose Maria Cordova International Airport
03:58
PTY Tocumen International Airport
1h 33m Direct
Trip.com
$182
View this ticket
16 Nov 2026, Mon
Copa Airlines CM 757
18:45
MDE Jose Maria Cordova International Airport
20:14
PTY Tocumen International Airport
1h 29m Direct
Trip.com
$185
View this ticket
Route characteristics
Distance
532 km
Flight time
1h 8m
Time difference
+0h
Minimum price
from $181 (17.11.2026)
Average price
$187
Maximum price
$202
Departures per week
1
Cheapest day
Tuesday
Departure airports (1)
MDE Jose Maria Cordova International Airport
Arrival airports (1)
PTY Tocumen International Airport
Airlines (2)
CM Copa Airlines AV avianca airlines
Agencies (3)
Tickets Trip.com City.Travel
Prices by day of week
Monday
$185
avg $185
Tuesday
$181
avg $181
Cheapest
Thursday
$182
avg $182
Airlines — cheapest prices 2
Copa Airlines
Copa Airlines
8 flights · 7 days
$181
avianca airlines
avianca airlines
2 flights · 2 days
$220
Where to buy tickets 3
Tickets
3 tickets · 2 days
from $181
Trip.com
6 tickets · 5 days
from $182
City.Travel
1 tickets · 1 days
from $224
Airports

From — Medellin (1)

  • MDE Jose Maria Cordova International Airport

To — Panama City (1)

  • PTY Tocumen International Airport
Other destinations from Medellin
Bogota
CO
Cali
CO
Bucaramanga
CO
Monteria
CO
Pereira
CO
Apartado
CO
Bahia Solano
CO
Quibdo
CO
Ibague
CO
Curacao
CW
Miami
US · Hub
Barranquilla
CO
Frequently asked questions about the route Medellin — Panama City
How long is the flight from Medellin to Panama City?
Approximate flight time — 1h 8m. This is an average for a direct flight. With connections, the time may be longer.
What is the distance from Medellin to Panama City?
The straight-line distance — 532 km.
How much do flights from Medellin to Panama City cost?
The minimum price over 3 months — from $181 on 17.11.2026.
What is the average ticket price?
The average price — $187. Range: $181 — $202.
What is the time difference between Medellin and Panama City?
The difference — +0h.
From which airports does Medellin operate flights?
From Medellin: MDE (Jose Maria Cordova International Airport).
To which airports in Panama City do flights arrive?
To Panama City: PTY (Tocumen International Airport).
Which airlines fly this route?
This route is served by 2 airlines: Copa Airlines, avianca airlines.
Are there direct flights?
Yes, there are direct flights. Minimum direct price — from $181. Total direct flights found: 3.
Which day of the week is cheapest?
The cheapest day of the week — Tuesday.
When is the best time to buy tickets?
Optimal — 1–3 months before departure. Check the calendar above — it shows the best dates.
How do I book flights?
Click "View this ticket" on any flight card — you'll be redirected to the booking page with this specific ticket pre-selected.
About the route Medellin — Panama City

Flights Medellin — Panama City is a popular route. The straight-line distance is 532 km. Flight time 1h 8m. Time difference +0h.

From Medellin (MDE) flights depart from 1 airport: MDE. To Panama City (PTY) — 1 arrival airport: PTY.

2 airlines operate on this route: Copa Airlines, avianca airlines.

The minimum price for the next 3 months — from $181 (17.11.2026). The cheapest dates are highlighted in the calendar above.

The average ticket price — $187, ranging from $181 to $202. Book 1–3 months in advance to get the best deals.

Cheapest day to fly — Tuesday.

Other destinations in Panama from Medellin
Bocas Del Toro
PA

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