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Cheap flights Mexico City — Panama City

Mexico City (MEX, MX) Panama City (PTY, PA)
from $234 2 407 km ~3h 20m 9 flights found 4 airlines cheapest on Wednesday
Reverse route
How many travellers?
Adults
12+ years
1
Children
2–11 years
0
Infants
under 2
0
Choose your departure date
Cheapest: $234 on 14.11.2026
Prices shown are from searches by other travellers over the last 24 hours. Missing a date? Click any day — we'll find tickets anyway.
November 2026
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December 2026
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January 2027
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Prices found for 2 of 90 days. Prices update as more travellers search. Click any date to search live.
Depart
—
Return
—
Cheapest flights found
14 Nov 2026, Sat
Aeromexico AM 464
17:50
MEX Benito Juarez International Airport
21:46
PTY Tocumen International Airport
3h 56m Direct
Trip.com
$234
View this ticket
14 Nov 2026, Sat
avianca airlines AV 23
08:20
MEX Benito Juarez International Airport
14:55
PTY Tocumen International Airport
6h 35m 1 stop
Aviakassa
$420
View this ticket
13 Nov 2026, Fri
Copa Airlines CM 857
11:00
MEX Benito Juarez International Airport
14:44
PTY Tocumen International Airport
3h 44m Direct
Aviakassa
$576
View this ticket
Route characteristics
Distance
2 407 km
Flight time
3h 20m
Time difference
+1h
Minimum price
from $234 (14.11.2026)
Average price
$405
Maximum price
$576
Departures per week
1
Cheapest day
Wednesday
Departure airports (2)
MEX Benito Juarez International Airport TLC Toluca International Airport
Arrival airports (1)
PTY Tocumen International Airport
Airlines (4)
CM Copa Airlines AM Aeromexico Y4 Volaris AV avianca airlines
Agencies (4)
Farera Trip.com Kupi.com Aviakassa
Prices by day of week
Friday
$576
avg $576
Saturday
$234
avg $327
Airlines — cheapest prices 4
Copa Airlines
Copa Airlines
5 flights · 5 days
$216
Aeromexico
Aeromexico
2 flights · 2 days
$234
Volaris
Volaris
Low-cost 1 flights · 1 days
$388
avianca airlines
avianca airlines
1 flights · 1 days
$420
Where to buy tickets 4
Farera
2 tickets · 2 days
from $216
Trip.com
4 tickets · 4 days
from $231
Kupi.com
1 tickets · 1 days
from $388
Aviakassa
2 tickets · 2 days
from $420
Airports

From — Mexico City (2)

  • MEX Benito Juarez International Airport
  • TLC Toluca International Airport

To — Panama City (1)

  • PTY Tocumen International Airport
Other destinations from Mexico City
Acapulco
MX
Dallas
US · Hub
San Jose Del Cabo
MX
San Antonio
US
Cancun
MX
Ixtapa
MX
Puerto Vallarta
MX
Guadalajara
MX
Fort Lauderdale
US
Monterrey
MX
Ciudad Obregon
MX
Chetumal
MX
Frequently asked questions about the route Mexico City — Panama City
How long is the flight from Mexico City to Panama City?
Approximate flight time — 3h 20m. This is an average for a direct flight. With connections, the time may be longer.
What is the distance from Mexico City to Panama City?
The straight-line distance — 2 407 km.
How much do flights from Mexico City to Panama City cost?
The minimum price over 3 months — from $234 on 14.11.2026.
What is the average ticket price?
The average price — $405. Range: $234 — $576.
What is the time difference between Mexico City and Panama City?
The difference — +1h.
From which airports does Mexico City operate flights?
From Mexico City: MEX (Benito Juarez International Airport), TLC (Toluca International Airport).
To which airports in Panama City do flights arrive?
To Panama City: PTY (Tocumen International Airport).
Which airlines fly this route?
This route is served by 4 airlines: Copa Airlines, Aeromexico, Volaris, avianca airlines.
Are there direct flights?
Yes, there are direct flights. Minimum direct price — from $234. Total direct flights found: 2.
Which day of the week is cheapest?
The cheapest day of the week — Wednesday.
When is the best time to buy tickets?
Optimal — 1–3 months before departure. Check the calendar above — it shows the best dates.
How do I book flights?
Click "View this ticket" on any flight card — you'll be redirected to the booking page with this specific ticket pre-selected.
About the route Mexico City — Panama City

Flights Mexico City — Panama City is a popular route. The straight-line distance is 2 407 km. Flight time 3h 20m. Time difference +1h.

From Mexico City (MEX) flights depart from 2 airports: MEX, TLC. To Panama City (PTY) — 1 arrival airport: PTY.

4 airlines operate on this route: Copa Airlines, Aeromexico, Volaris, avianca airlines.

The minimum price for the next 3 months — from $234 (14.11.2026). The cheapest dates are highlighted in the calendar above.

The average ticket price — $405, ranging from $234 to $576. Book 1–3 months in advance to get the best deals.

Cheapest day to fly — Wednesday.

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