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Cheap flights Panama City — Sao Paulo

Panama City (PTY, PA) Sao Paulo (GRU, BR)
from $303 5 086 km ~6h 29m 16 flights found 2 airlines cheapest on Friday
Reverse route
How many travellers?
Adults
12+ years
1
Children
2–11 years
0
Infants
under 2
0
Choose your departure date
Cheapest: $303 on 14.12.2026
Prices shown are from searches by other travellers over the last 24 hours. Missing a date? Click any day — we'll find tickets anyway.
November 2026
Mo
Tu
We
Th
Fr
Sa
Su
December 2026
Mo
Tu
We
Th
Fr
Sa
Su
January 2027
Mo
Tu
We
Th
Fr
Sa
Su
Prices found for 36 of 90 days. Prices update as more travellers search. Click any date to search live.
Depart
—
Return
—
Cheapest flights found
14 Dec 2026, Mon
avianca airlines AV 057
02:10
PTY Tocumen International Airport
10:30
GRU Sao Paulo-Guarulhos International Airport
8h 20m 2 stops
Farera
$303
View this ticket
12 Dec 2026, Sat
avianca airlines AV 41
10:30
PTY Tocumen International Airport
19:55
GRU Sao Paulo-Guarulhos International Airport
9h 25m 2 stops
Farera
$322
View this ticket
20 Jan 2027, Wed
avianca airlines AV 61
00:10
PTY Tocumen International Airport
10:55
GRU Sao Paulo-Guarulhos International Airport
10h 45m 2 stops
City.Travel
$362
View this ticket
25 Dec 2026, Fri
avianca airlines AV 41
10:30
PTY Tocumen International Airport
20:00
GRU Sao Paulo-Guarulhos International Airport
9h 30m 2 stops
City.Travel
$380
View this ticket
22 Jan 2027, Fri
avianca airlines AV 59
18:05
PTY Tocumen International Airport
02:05
GRU Sao Paulo-Guarulhos International Airport
8h 1 stop
City.Travel
$459
View this ticket
15 Jan 2027, Fri
avianca airlines AV 41
10:30
PTY Tocumen International Airport
18:25
GRU Sao Paulo-Guarulhos International Airport
7h 55m 1 stop
City.Travel
$488
View this ticket
Route characteristics
Distance
5 086 km
Flight time
6h 29m
Time difference
+2h
Minimum price
from $303 (14.12.2026)
Average price
$487
Maximum price
$1 093
Departures per week
1
Cheapest day
Friday
Departure airports (1)
PTY Tocumen International Airport
Arrival airports (1)
GRU Sao Paulo-Guarulhos International Airport
Airlines (2)
AV avianca airlines CM Copa Airlines
Agencies (6)
Farera City.Travel Aviakassa Tickets Авиасейлс Trip.com
Prices by day of week
Monday
$303
avg $303
Wednesday
$362
avg $362
Friday
$380
avg $442
Cheapest
Saturday
$322
avg $322
Price trend by month
December 2026
from $303
avg $335
3 flights
January 2027
from $362
avg $436
3 flights
Airlines — cheapest prices 2
avianca airlines
avianca airlines
8 flights · 8 days
$303
Copa Airlines
Copa Airlines
8 flights · 8 days
$634
Where to buy tickets 6
Farera
2 tickets · 2 days
from $303
City.Travel
5 tickets · 5 days
from $362
Aviakassa
3 tickets · 3 days
from $634
Tickets
2 tickets · 2 days
from $646
Авиасейлс
1 tickets · 1 days
from $646
Trip.com
3 tickets · 3 days
from $1 048
Airports

From — Panama City (1)

  • PTY Tocumen International Airport

To — Sao Paulo (1)

  • GRU Sao Paulo-Guarulhos International Airport
Other destinations from Panama City
Bocas Del Toro
PA
David
PA
Jaque
PA
Playon Chico
PA
Barcelona
VE
Miami
US · Hub
Cancun
MX
Guadalajara
MX
Mexico City
MX
Bogota
CO
Medellin
CO
Amsterdam
NL · Hub
Frequently asked questions about the route Panama City — Sao Paulo
How long is the flight from Panama City to Sao Paulo?
Approximate flight time — 6h 29m. This is an average for a direct flight. With connections, the time may be longer.
What is the distance from Panama City to Sao Paulo?
The straight-line distance — 5 086 km.
How much do flights from Panama City to Sao Paulo cost?
The minimum price over 3 months — from $303 on 14.12.2026.
What is the average ticket price?
The average price — $487. Range: $303 — $1 093.
What is the time difference between Panama City and Sao Paulo?
The difference — +2h.
From which airports does Panama City operate flights?
From Panama City: PTY (Tocumen International Airport).
To which airports in Sao Paulo do flights arrive?
To Sao Paulo: GRU (Sao Paulo-Guarulhos International Airport).
Which airlines fly this route?
This route is served by 2 airlines: avianca airlines, Copa Airlines.
Which day of the week is cheapest?
The cheapest day of the week — Friday.
When is the best time to buy tickets?
Optimal — 1–3 months before departure. Check the calendar above — it shows the best dates.
How do I book flights?
Click "View this ticket" on any flight card — you'll be redirected to the booking page with this specific ticket pre-selected.
About the route Panama City — Sao Paulo

Flights Panama City — Sao Paulo is a popular route. The straight-line distance is 5 086 km. Flight time 6h 29m. Time difference +2h.

From Panama City (PTY) flights depart from 1 airport: PTY. To Sao Paulo (GRU) — 1 arrival airport: GRU.

2 airlines operate on this route: avianca airlines, Copa Airlines.

The minimum price for the next 3 months — from $303 (14.12.2026). The cheapest dates are highlighted in the calendar above.

The average ticket price — $487, ranging from $303 to $1 093. Book 1–3 months in advance to get the best deals.

Cheapest day to fly — Friday.

Other destinations in Brazil from Panama City
Brasilia
BR
Manaus
BR
Porto Alegre
BR
Recife
BR
Sao Paulo
BR
Salvador
BR
Rio de Janeiro
BR
Florianopolis
BR

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