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Cheap flights Panama City — Santa Cruz

Panama City (PTY, PA) Santa Cruz (VVI, BO)
from $558 3 481 km ~4h 36m 3 flights found 1 airlines cheapest on Thursday
Reverse route
How many travellers?
Adults
12+ years
1
Children
2–11 years
0
Infants
under 2
0
Choose your departure date
Cheapest: $558 on 28.01.2027
Prices shown are from searches by other travellers over the last 24 hours. Missing a date? Click any day — we'll find tickets anyway.
November 2026
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December 2026
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January 2027
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Prices found for 2 of 90 days. Prices update as more travellers search. Click any date to search live.
Depart
—
Return
—
Cheapest flights found
28 Jan 2027, Thu
Copa Airlines CM 131
20:01
PTY Tocumen International Airport
02:10
VVI Viru Viru International Airport
6h 9m 1 stop
City.Travel
$558
View this ticket
29 Jan 2027, Fri
Copa Airlines CM 489
03:00
PTY Tocumen International Airport
09:15
VVI Viru Viru International Airport
6h 15m 1 stop
City.Travel
$558
View this ticket
29 Jan 2027, Fri
Copa Airlines CM 127
00:40
PTY Tocumen International Airport
05:46
VVI Viru Viru International Airport
5h 6m Direct
Trip.com
$733
View this ticket
Route characteristics
Distance
3 481 km
Flight time
4h 36m
Time difference
+1h
Minimum price
from $558 (28.01.2027)
Average price
$558
Maximum price
$558
Cheapest day
Thursday
Departure airports (1)
PTY Tocumen International Airport
Arrival airports (1)
VVI Viru Viru International Airport
Airlines (1)
CM Copa Airlines
Agencies (2)
City.Travel Trip.com
Prices by day of week
Thursday
$558
avg $558
Cheapest
Friday
$558
avg $646
Airlines — cheapest prices 1
Copa Airlines
Copa Airlines
3 flights · 2 days
$558
Where to buy tickets 2
City.Travel
2 tickets · 2 days
from $558
Trip.com
1 tickets · 1 days
from $733
Airports

From — Panama City (1)

  • PTY Tocumen International Airport

To — Santa Cruz (1)

  • VVI Viru Viru International Airport
Other destinations from Panama City
Bocas Del Toro
PA
David
PA
Jaque
PA
Playon Chico
PA
Barcelona
VE
Miami
US · Hub
Cancun
MX
Guadalajara
MX
Mexico City
MX
Bogota
CO
Medellin
CO
Amsterdam
NL · Hub
Frequently asked questions about the route Panama City — Santa Cruz
How long is the flight from Panama City to Santa Cruz?
Approximate flight time — 4h 36m. This is an average for a direct flight. With connections, the time may be longer.
What is the distance from Panama City to Santa Cruz?
The straight-line distance — 3 481 km.
How much do flights from Panama City to Santa Cruz cost?
The minimum price over 3 months — from $558 on 28.01.2027.
What is the average ticket price?
The average price — $558. Range: $558 — $558.
What is the time difference between Panama City and Santa Cruz?
The difference — +1h.
From which airports does Panama City operate flights?
From Panama City: PTY (Tocumen International Airport).
To which airports in Santa Cruz do flights arrive?
To Santa Cruz: VVI (Viru Viru International Airport).
Which airlines fly this route?
This route is served by 1 airline: Copa Airlines.
Are there direct flights?
Yes, there are direct flights. Minimum direct price — from $733. Total direct flights found: 1.
Which day of the week is cheapest?
The cheapest day of the week — Thursday.
When is the best time to buy tickets?
Optimal — 1–3 months before departure. Check the calendar above — it shows the best dates.
How do I book flights?
Click "View this ticket" on any flight card — you'll be redirected to the booking page with this specific ticket pre-selected.
About the route Panama City — Santa Cruz

Flights Panama City — Santa Cruz is a popular route. The straight-line distance is 3 481 km. Flight time 4h 36m. Time difference +1h.

From Panama City (PTY) flights depart from 1 airport: PTY. To Santa Cruz (VVI) — 1 arrival airport: VVI.

1 airline operate on this route: Copa Airlines.

The minimum price for the next 3 months — from $558 (28.01.2027). The cheapest dates are highlighted in the calendar above.

The average ticket price — $558, ranging from $558 to $558. Book 1–3 months in advance to get the best deals.

Cheapest day to fly — Thursday.

Other destinations in Bolivia from Panama City
La Paz
BO
Santa Cruz
BO

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