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Cheap flights San Francisco — Panama City

from $457 5 350 km ~6h 48m 2 flights found 2 airlines cheapest on Wednesday
How many travellers?
Adults
12+ years
1
Children
2–11 years
0
Infants
under 2
0
Choose your departure date
Cheapest: $457 on 02.12.2026
Prices shown are from searches by other travellers over the last 24 hours. Missing a date? Click any day — we'll find tickets anyway.
November 2026
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December 2026
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January 2027
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Prices found for 1 of 90 days. Prices update as more travellers search. Click any date to search live.
Depart
—
Return
—
Cheapest flights found
02 Dec 2026, Wed
Frontier Airlines F9 4158
21:35
SFO San Francisco International Airport
06:55
PTY Tocumen International Airport
9h 20m 2 stops
View this ticket
02 Dec 2026, Wed
Copa Airlines CM 383
11:33
SFO San Francisco International Airport
18:46
PTY Tocumen International Airport
7h 13m Direct
View this ticket
Route characteristics
Distance
5 350 km
Flight time
6h 48m
Time difference
+2h
Minimum price
from $457 (02.12.2026)
Average price
$457
Maximum price
$457
Cheapest day
Wednesday
Departure airports (1)
SFO San Francisco International Airport
Arrival airports (1)
PTY Tocumen International Airport
Airlines (2)
F9 Frontier Airlines CM Copa Airlines
Agencies (2)
Kiwi.com Trip.com
Airlines — cheapest prices 2
Frontier Airlines
Frontier Airlines
Low-cost 1 flights · 1 days
$457
Copa Airlines
Copa Airlines
1 flights · 1 days
$919
Where to buy tickets 2
Kiwi.com
1 tickets · 1 days
from $457
Trip.com
1 tickets · 1 days
from $919
Airports

From — San Francisco (1)

  • SFO San Francisco International Airport

To — Panama City (1)

  • PTY Tocumen International Airport
Other destinations from San Francisco
Frequently asked questions about the route San Francisco — Panama City
How long is the flight from San Francisco to Panama City?
Approximate flight time — 6h 48m. This is an average for a direct flight. With connections, the time may be longer.
What is the distance from San Francisco to Panama City?
The straight-line distance — 5 350 km.
How much do flights from San Francisco to Panama City cost?
The minimum price over 3 months — from $457 on 02.12.2026.
What is the average ticket price?
The average price — $457. Range: $457 — $457.
What is the time difference between San Francisco and Panama City?
The difference — +2h.
From which airports does San Francisco operate flights?
From San Francisco: SFO (San Francisco International Airport).
To which airports in Panama City do flights arrive?
To Panama City: PTY (Tocumen International Airport).
Which airlines fly this route?
This route is served by 2 airlines: Frontier Airlines, Copa Airlines.
Are there direct flights?
Yes, there are direct flights. Minimum direct price — from $919. Total direct flights found: 1.
Which day of the week is cheapest?
The cheapest day of the week — Wednesday.
When is the best time to buy tickets?
Optimal — 1–3 months before departure. Check the calendar above — it shows the best dates.
How do I book flights?
Click "View this ticket" on any flight card — you'll be redirected to the booking page with this specific ticket pre-selected.
About the route San Francisco — Panama City

Flights San Francisco — Panama City is a popular route. The straight-line distance is 5 350 km. Flight time 6h 48m. Time difference +2h.

From San Francisco (SFO) flights depart from 1 airport: SFO. To Panama City (PTY) — 1 arrival airport: PTY.

2 airlines operate on this route: Frontier Airlines, Copa Airlines.

The minimum price for the next 3 months — from $457 (02.12.2026). The cheapest dates are highlighted in the calendar above.

The average ticket price — $457, ranging from $457 to $457. Book 1–3 months in advance to get the best deals.

Cheapest day to fly — Wednesday.