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Cheap flights Guayaquil — Santiago

Guayaquil (GYE, EC) Santiago (SCL, CL)
from $322 3 606 km ~4h 45m 8 flights found 4 airlines cheapest on Tuesday
Reverse route
How many travellers?
Adults
12+ years
1
Children
2–11 years
0
Infants
under 2
0
Choose your departure date
Cheapest: $322 on 30.01.2027
Prices shown are from searches by other travellers over the last 24 hours. Missing a date? Click any day — we'll find tickets anyway.
November 2026
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December 2026
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January 2027
Mo
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Prices found for 2 of 90 days. Prices update as more travellers search. Click any date to search live.
Depart
—
Return
—
Cheapest flights found
30 Jan 2027, Sat
Aerolineas Argentinas AR 8421
17:05
GYE Jose Joaquin de Olmedo Airport
22:30
SCL Arturo Merino Benitez Airport
5h 25m 1 stop
Trip.com
$322
View this ticket
31 Jan 2027, Sun
LATAM Airlines Group LA 1447
01:28
GYE Jose Joaquin de Olmedo Airport
06:21
SCL Arturo Merino Benitez Airport
4h 53m Direct
Trip.com
$322
View this ticket
Route characteristics
Distance
3 606 km
Flight time
4h 45m
Time difference
+2h
Minimum price
from $322 (30.01.2027)
Average price
$322
Maximum price
$322
Departures per week
1
Cheapest day
Tuesday
Departure airports (1)
GYE Jose Joaquin de Olmedo Airport
Arrival airports (1)
SCL Arturo Merino Benitez Airport
Airlines (4)
CM Copa Airlines AV avianca airlines LA LATAM Airlines Group AR Aerolineas Argentinas
Agencies (4)
Kiwi.com Mytrip.com Flightnetwork Trip.com
Prices by day of week
Saturday
$322
avg $322
Sunday
$322
avg $322
Airlines — cheapest prices 4
Copa Airlines
Copa Airlines
2 flights · 2 days
$267
avianca airlines
avianca airlines
1 flights · 1 days
$278
LATAM Airlines Group
LATAM Airlines Group
4 flights · 4 days
$300
Aerolineas Argentinas
Aerolineas Argentinas
1 flights · 1 days
$322
Where to buy tickets 4
Kiwi.com
3 tickets · 3 days
from $267
Mytrip.com
1 tickets · 1 days
from $300
Flightnetwork
2 tickets · 2 days
from $313
Trip.com
2 tickets · 2 days
from $322
Airports

From — Guayaquil (1)

  • GYE Jose Joaquin de Olmedo Airport

To — Santiago (1)

  • SCL Arturo Merino Benitez Airport
Other destinations from Guayaquil
Amsterdam
NL · Hub
Asuncion
PY
Athens
GR
Baku
AZ
Barcelona
ES · Hub
Barcelona
VE
Bogota
CO
Brussels
BE · Hub
Buenos Aires
AR
Caracas
VE
Cali
CO
Cartagena
CO
Frequently asked questions about the route Guayaquil — Santiago
How long is the flight from Guayaquil to Santiago?
Approximate flight time — 4h 45m. This is an average for a direct flight. With connections, the time may be longer.
What is the distance from Guayaquil to Santiago?
The straight-line distance — 3 606 km.
How much do flights from Guayaquil to Santiago cost?
The minimum price over 3 months — from $322 on 30.01.2027.
What is the average ticket price?
The average price — $322. Range: $322 — $322.
What is the time difference between Guayaquil and Santiago?
The difference — +2h.
From which airports does Guayaquil operate flights?
From Guayaquil: GYE (Jose Joaquin de Olmedo Airport).
To which airports in Santiago do flights arrive?
To Santiago: SCL (Arturo Merino Benitez Airport).
Which airlines fly this route?
This route is served by 4 airlines: Copa Airlines, avianca airlines, LATAM Airlines Group, Aerolineas Argentinas.
Are there direct flights?
Yes, there are direct flights. Minimum direct price — from $322. Total direct flights found: 1.
Which day of the week is cheapest?
The cheapest day of the week — Tuesday.
When is the best time to buy tickets?
Optimal — 1–3 months before departure. Check the calendar above — it shows the best dates.
How do I book flights?
Click "View this ticket" on any flight card — you'll be redirected to the booking page with this specific ticket pre-selected.
About the route Guayaquil — Santiago

Flights Guayaquil — Santiago is a popular route. The straight-line distance is 3 606 km. Flight time 4h 45m. Time difference +2h.

From Guayaquil (GYE) flights depart from 1 airport: GYE. To Santiago (SCL) — 1 arrival airport: SCL.

4 airlines operate on this route: Copa Airlines, avianca airlines, LATAM Airlines Group, Aerolineas Argentinas.

The minimum price for the next 3 months — from $322 (30.01.2027). The cheapest dates are highlighted in the calendar above.

The average ticket price — $322, ranging from $322 to $322. Book 1–3 months in advance to get the best deals.

Cheapest day to fly — Tuesday.

Other destinations in Chile from Guayaquil
Puerto Montt
CL
Puerto Natales
CL

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