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Cheap flights Santiago — Guayaquil

Santiago (SCL, CL) Guayaquil (GYE, EC)
from $251 3 606 km ~4h 45m 2 flights found 2 airlines cheapest on Thursday
Reverse route
How many travellers?
Adults
12+ years
1
Children
2–11 years
0
Infants
under 2
0
Choose your departure date
Cheapest: $251 on 26.11.2026
Prices shown are from searches by other travellers over the last 24 hours. Missing a date? Click any day — we'll find tickets anyway.
November 2026
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December 2026
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January 2027
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Prices found for 2 of 90 days. Prices update as more travellers search. Click any date to search live.
Depart
—
Return
—
Cheapest flights found
26 Nov 2026, Thu
LATAM Airlines Group LA 508
02:25
SCL Arturo Merino Benitez Airport
08:20
GYE Jose Joaquin de Olmedo Airport
5h 55m 1 stop
Clickavia
$251
View this ticket
25 Nov 2026, Wed
LATAM Airlines Ecuador XL 1446
07:45
SCL Arturo Merino Benitez Airport
13:03
GYE Jose Joaquin de Olmedo Airport
5h 18m Direct
Trip.com
$285
View this ticket
Route characteristics
Distance
3 606 km
Flight time
4h 45m
Time difference
-2h
Minimum price
from $251 (26.11.2026)
Average price
$268
Maximum price
$285
Cheapest day
Thursday
Departure airports (1)
SCL Arturo Merino Benitez Airport
Arrival airports (1)
GYE Jose Joaquin de Olmedo Airport
Airlines (2)
LA LATAM Airlines Group XL LATAM Airlines Ecuador
Agencies (2)
Clickavia Trip.com
Prices by day of week
Wednesday
$285
avg $285
Thursday
$251
avg $251
Cheapest
Airlines — cheapest prices 2
LATAM Airlines Group
LATAM Airlines Group
1 flights · 1 days
$251
LATAM Airlines Ecuador
LATAM Airlines Ecuador
1 flights · 1 days
$285
Where to buy tickets 2
Clickavia
1 tickets · 1 days
from $251
Trip.com
1 tickets · 1 days
from $285
Airports

From — Santiago (1)

  • SCL Arturo Merino Benitez Airport

To — Guayaquil (1)

  • GYE Jose Joaquin de Olmedo Airport
Other destinations from Santiago
Adelaide
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ES · Hub
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KZ
Amsterdam
NL · Hub
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Saint John's
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Arequipa
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Arica
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Asuncion
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Atlanta
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Manama
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Frequently asked questions about the route Santiago — Guayaquil
How long is the flight from Santiago to Guayaquil?
Approximate flight time — 4h 45m. This is an average for a direct flight. With connections, the time may be longer.
What is the distance from Santiago to Guayaquil?
The straight-line distance — 3 606 km.
How much do flights from Santiago to Guayaquil cost?
The minimum price over 3 months — from $251 on 26.11.2026.
What is the average ticket price?
The average price — $268. Range: $251 — $285.
What is the time difference between Santiago and Guayaquil?
The difference — -2h.
From which airports does Santiago operate flights?
From Santiago: SCL (Arturo Merino Benitez Airport).
To which airports in Guayaquil do flights arrive?
To Guayaquil: GYE (Jose Joaquin de Olmedo Airport).
Which airlines fly this route?
This route is served by 2 airlines: LATAM Airlines Group, LATAM Airlines Ecuador.
Are there direct flights?
Yes, there are direct flights. Minimum direct price — from $285. Total direct flights found: 1.
Which day of the week is cheapest?
The cheapest day of the week — Thursday.
When is the best time to buy tickets?
Optimal — 1–3 months before departure. Check the calendar above — it shows the best dates.
How do I book flights?
Click "View this ticket" on any flight card — you'll be redirected to the booking page with this specific ticket pre-selected.
About the route Santiago — Guayaquil

Flights Santiago — Guayaquil is a popular route. The straight-line distance is 3 606 km. Flight time 4h 45m. Time difference -2h.

From Santiago (SCL) flights depart from 1 airport: SCL. To Guayaquil (GYE) — 1 arrival airport: GYE.

2 airlines operate on this route: LATAM Airlines Group, LATAM Airlines Ecuador.

The minimum price for the next 3 months — from $251 (26.11.2026). The cheapest dates are highlighted in the calendar above.

The average ticket price — $268, ranging from $251 to $285. Book 1–3 months in advance to get the best deals.

Cheapest day to fly — Thursday.

Other destinations in Ecuador from Santiago
Galapagos Islands
EC
Quito
EC

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